Serious Allergic Reactions. Promethazine/phenylephrine/codeine could cause allergic reactions, that may be severe. Stop getting promethazine/phenylephrine/codeine and obtain help immediately In case you have any of the next indicators of a serious allergic response.
Respiratory melancholy happened just after the youngsters obtained An array of a single to eighteen doses, using a median of five doses. The most frequently described codeine-made up of medicines in the situations were acetaminophen with codeine utilized for ache, and promethazine with codeine (with or with no phenylephrine) utilized for cough and chilly.
Promethazine is additive into the depressant results of codeine. It really is challenging to figure out what constitutes a standard toxic or lethal dose. Even so, the lethal oral dose of codeine in an Grownup is noted to become inside the number of 0.5 to 1.0 gram. Infants and youngsters are considered to be fairly far more delicate to opiates on the physique-excess weight foundation. Elderly people also are comparatively intolerant to opiates.
Promethazine hydrochloride occurs like a white to faint yellow, almost odorless, crystalline powder which slowly and gradually oxidizes and turns blue on extended publicity to air.
Codeine is surely an opioid analgesic applied to deal with moderate to serious discomfort when using an opioid is indicated.
Stimulation might be obvious, particularly in kids and geriatric people. Convulsions could rarely arise. A paradoxical-kind reaction continues to be noted in children getting solitary doses of 75 mg to a hundred twenty five mg orally, characterised by hyperexcitability and nightmares.
Codeine: In people acquiring MAO inhibitors, an Original compact take a look at dose is advisable to permit observation of any too here much narcotic outcomes or MAOI interaction.
Promethazine/phenylephrine/codeine can have an effect on your alertness or coordination. Usually do not drive or do other pursuits that need alertness or coordination until finally you understand how the medicine impacts you.
Asthma Together with other Respiratory Disorders: Narcotic analgesics or cough suppressants, such as codeine, should not be Employed in asthmatic people (see CONTRAINDICATIONS). Nor must they be Utilized in acute febrile ailment affiliated with successful cough or in Serious respiratory ailment where interference with ability to apparent the tracheobronchial tree of secretions might have a deleterious impact on the affected person’s respiratory operate. Hypotensive Result: Codeine could create orthostatic hypotension in ambulatory clients.
常見之不良反應有：瘙癢、噁心、嘔吐、昏睡、口乾、瞳孔縮小、姿態性低血壓（orthostatic hypotension）、小便不暢、便秘。
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People who find themselves 65 and older is usually at better threat for a few side effects from promethazine/phenylephrine/codeine. Check with your Health care company regarding your challenges When you are With this age group.
Cough is usually secondary to an infection, not serious, and typically will get well on its own so treatment method might not be vital.
The level of medicine that you choose to acquire is determined by the toughness in the drugs. Also, the amount of doses you're taking on a daily basis, some time allowed involving doses, and also the period of time you go ahead and take drugs depend upon the medical difficulty for which you are utilizing the drugs.